HuLG001697

Entrez Gene ID

2549

Official Gene Symbol

GAB1

Gene name

GRB2-associated binding protein 1

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q31.21

Known cancer genes

Yes

Protein products

GRB2-associated-binding protein 1

cDNA FLJ12080 fis, clone HEMBB1002477, highly similar to Human Grb2-associated binder-1 mRNA

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:4066
MIM:604439
Ensembl:ENSG00000109458
HPRD:05116
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0005070

SH3/SH2 adaptor activity

GO:0005515

protein binding

GO:0005829

cytosol

GO:0007173

epidermal growth factor receptor signaling pathway

GO:0008283

cell proliferation

GO:0008286

insulin receptor signaling pathway

GO:0008543

fibroblast growth factor receptor signaling pathway