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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001719

Entrez Gene ID

2572

Official Gene Symbol

GAD2

Synonyms

GAD65|MGC161605|MGC161607

Gene name

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

Gene Type

protein-coding

Chromosome

10

Genomics Location

10p11.23

Known cancer genes

Yes

Protein products

Glutamate decarboxylase 2

Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:4093
MIM:138275
Ensembl:ENSG00000136750
HPRD:11817
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000139

Golgi membrane

GO:0004351

glutamate decarboxylase activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006540

glutamate decarboxylation to succinate

GO:0007268

synaptic transmission

GO:0007269

neurotransmitter secretion

GO:0016023

cytoplasmic membrane-bounded vesicle

GO:0016829

lyase activity

GO:0019752

carboxylic acid metabolic process

GO:0030054

cell junction

GO:0030170

pyridoxal phosphate binding

GO:0030424

axon

GO:0030672

synaptic vesicle membrane

GO:0031225

anchored to membrane

GO:0042136

neurotransmitter biosynthetic process

GO:0042493

response to drug

GO:0042734

presynaptic membrane

GO:0045202

synapse

GO:0048471

perinuclear region of cytoplasm

GO:0061202

clathrin sculpted gamma-aminobutyric acid transport vesicle membrane