Gene basic information
LiverAtlas Gene ID |
HuLG001719 |
Entrez Gene ID |
|
Official Gene Symbol |
GAD2 |
Synonyms |
GAD65|MGC161605|MGC161607 |
Gene name |
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
Gene Type |
protein-coding |
Chromosome |
10 |
Genomics Location |
10p11.23 |
Known cancer genes |
Yes |
Protein products |
Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) |
Related liver disease name |
|
Database cross reference |
HGNC:4093
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000139 |
Golgi membrane |
GO:0004351 |
glutamate decarboxylase activity |
GO:0005515 |
protein binding |
GO:0005737 |
cytoplasm |
GO:0005794 |
Golgi apparatus |
GO:0005829 |
cytosol |
GO:0005886 |
plasma membrane |
GO:0006540 |
glutamate decarboxylation to succinate |
GO:0007268 |
synaptic transmission |
GO:0007269 |
neurotransmitter secretion |
GO:0016023 |
cytoplasmic membrane-bounded vesicle |
GO:0016829 |
lyase activity |
GO:0019752 |
carboxylic acid metabolic process |
GO:0030054 |
cell junction |
GO:0030170 |
pyridoxal phosphate binding |
GO:0030424 |
axon |
GO:0030672 |
synaptic vesicle membrane |
GO:0031225 |
anchored to membrane |
GO:0042136 |
neurotransmitter biosynthetic process |
GO:0042493 |
response to drug |
GO:0042734 |
presynaptic membrane |
GO:0045202 |
synapse |
GO:0048471 |
perinuclear region of cytoplasm |
GO:0061202 |
clathrin sculpted gamma-aminobutyric acid transport vesicle membrane |