Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001750

Entrez Gene ID

2625

Official Gene Symbol

GATA3

Synonyms

HDR|MGC2346|MGC5199|MGC5445

Gene name

GATA binding protein 3

Gene Type

protein-coding

Chromosome

10

Genomics Location

10p15

Known cancer genes

Yes

Protein products

Trans-acting T-cell-specific transcription factor GATA-3

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:4172
MIM:131320
Ensembl:ENSG00000107485
HPRD:00572
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000790

nuclear chromatin

GO:0000976

transcription regulatory region sequence-specific DNA binding

GO:0000987

core promoter proximal region sequence-specific DNA binding

GO:0001046

core promoter sequence-specific DNA binding

GO:0001709

cell fate determination

GO:0001822

kidney development

GO:0001823

mesonephros development

GO:0003180

aortic valve morphogenesis

GO:0003215

cardiac right ventricle morphogenesis

GO:0003281

ventricular septum development

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003713

transcription coactivator activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005730

nucleolus

GO:0006366

transcription from RNA polymerase II promoter

GO:0006952

defense response

GO:0007165

signal transduction

GO:0007596

blood coagulation

GO:0008134

transcription factor binding

GO:0008270

zinc ion binding

GO:0008285

negative regulation of cell proliferation

GO:0008584

male gonad development

GO:0009615

response to virus

GO:0009653

anatomical structure morphogenesis

GO:0009967

positive regulation of signal transduction

GO:0010595

positive regulation of endothelial cell migration

GO:0014065

phosphatidylinositol 3-kinase cascade

GO:0031929

TOR signaling cascade

GO:0032753

positive regulation of interleukin-4 production

GO:0033600

negative regulation of mammary gland epithelial cell proliferation

GO:0035457

cellular response to interferon-alpha

GO:0042035

regulation of cytokine biosynthetic process

GO:0042421

norepinephrine biosynthetic process

GO:0043583

ear development

GO:0043627

response to estrogen stimulus

GO:0044212

transcription regulatory region DNA binding

GO:0045582

positive regulation of T cell differentiation

GO:0045786

negative regulation of cell cycle

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046872

metal ion binding

GO:0048485

sympathetic nervous system development

GO:0048646

anatomical structure formation involved in morphogenesis

GO:0050728

negative regulation of inflammatory response

GO:0050852

T cell receptor signaling pathway

GO:0051897

positive regulation of protein kinase B signaling cascade

GO:0060037

pharyngeal system development

GO:0060065

uterus development

GO:0060231

mesenchymal to epithelial transition

GO:0060676

ureteric bud formation

GO:0061290

canonical Wnt receptor signaling pathway involved in metanephric kidney development

GO:0070888

E-box binding

GO:0071353

cellular response to interleukin-4

GO:0071356

cellular response to tumor necrosis factor

GO:0071837

HMG box domain binding

GO:0072107

positive regulation of ureteric bud formation

GO:0072178

nephric duct morphogenesis

GO:0072179

nephric duct formation

GO:0072182

regulation of nephron tubule epithelial cell differentiation

GO:0072676

lymphocyte migration

GO:2000146

negative regulation of cell motility

GO:2000352

negative regulation of endothelial cell apoptosis

GO:2000607

negative regulation of cell proliferation involved in mesonephros development

GO:2000611

positive regulation of thyroid hormone generation

GO:2000664

positive regulation of interleukin-5 secretion

GO:2000667

positive regulation of interleukin-13 secretion

GO:2000679

positive regulation of transcription regulatory region DNA binding

GO:2000683

regulation of cellular response to X-ray