Gene basic information
LiverAtlas Gene ID |
HuLG001750 |
Entrez Gene ID |
|
Official Gene Symbol |
GATA3 |
Synonyms |
HDR|MGC2346|MGC5199|MGC5445 |
Gene name |
GATA binding protein 3 |
Gene Type |
protein-coding |
Chromosome |
10 |
Genomics Location |
10p15 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:4172
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000790 |
nuclear chromatin |
GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
GO:0000987 |
core promoter proximal region sequence-specific DNA binding |
GO:0001046 |
core promoter sequence-specific DNA binding |
GO:0001709 |
cell fate determination |
GO:0001822 |
kidney development |
GO:0001823 |
mesonephros development |
GO:0003180 |
aortic valve morphogenesis |
GO:0003215 |
cardiac right ventricle morphogenesis |
GO:0003281 |
ventricular septum development |
GO:0003677 |
DNA binding |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
GO:0003713 |
transcription coactivator activity |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005654 |
nucleoplasm |
GO:0005730 |
nucleolus |
GO:0006366 |
transcription from RNA polymerase II promoter |
GO:0006952 |
defense response |
GO:0007165 |
signal transduction |
GO:0007596 |
blood coagulation |
GO:0008134 |
transcription factor binding |
GO:0008270 |
zinc ion binding |
GO:0008285 |
negative regulation of cell proliferation |
GO:0008584 |
male gonad development |
GO:0009615 |
response to virus |
GO:0009653 |
anatomical structure morphogenesis |
GO:0009967 |
positive regulation of signal transduction |
GO:0010595 |
positive regulation of endothelial cell migration |
GO:0014065 |
phosphatidylinositol 3-kinase cascade |
GO:0031929 |
TOR signaling cascade |
GO:0032753 |
positive regulation of interleukin-4 production |
GO:0033600 |
negative regulation of mammary gland epithelial cell proliferation |
GO:0035457 |
cellular response to interferon-alpha |
GO:0042035 |
regulation of cytokine biosynthetic process |
GO:0042421 |
norepinephrine biosynthetic process |
GO:0043583 |
ear development |
GO:0043627 |
response to estrogen stimulus |
GO:0044212 |
transcription regulatory region DNA binding |
GO:0045582 |
positive regulation of T cell differentiation |
GO:0045786 |
negative regulation of cell cycle |
GO:0045892 |
negative regulation of transcription, DNA-dependent |
GO:0045893 |
positive regulation of transcription, DNA-dependent |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046872 |
metal ion binding |
GO:0048485 |
sympathetic nervous system development |
GO:0048646 |
anatomical structure formation involved in morphogenesis |
GO:0050728 |
negative regulation of inflammatory response |
GO:0050852 |
T cell receptor signaling pathway |
GO:0051897 |
positive regulation of protein kinase B signaling cascade |
GO:0060037 |
pharyngeal system development |
GO:0060065 |
uterus development |
GO:0060231 |
mesenchymal to epithelial transition |
GO:0060676 |
ureteric bud formation |
GO:0061290 |
canonical Wnt receptor signaling pathway involved in metanephric kidney development |
GO:0070888 |
E-box binding |
GO:0071353 |
cellular response to interleukin-4 |
GO:0071356 |
cellular response to tumor necrosis factor |
GO:0071837 |
HMG box domain binding |
GO:0072107 |
positive regulation of ureteric bud formation |
GO:0072178 |
nephric duct morphogenesis |
GO:0072179 |
nephric duct formation |
GO:0072182 |
regulation of nephron tubule epithelial cell differentiation |
GO:0072676 |
lymphocyte migration |
GO:2000146 |
negative regulation of cell motility |
GO:2000352 |
negative regulation of endothelial cell apoptosis |
GO:2000607 |
negative regulation of cell proliferation involved in mesonephros development |
GO:2000611 |
positive regulation of thyroid hormone generation |
GO:2000664 |
positive regulation of interleukin-5 secretion |
GO:2000667 |
positive regulation of interleukin-13 secretion |
GO:2000679 |
positive regulation of transcription regulatory region DNA binding |
GO:2000683 |
regulation of cellular response to X-ray |