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Gene basic information

LiverAtlas Gene ID

HuLG001786

Entrez Gene ID

2668

Official Gene Symbol

GDNF

Synonyms

ATF1|ATF2|HFB1NGDNF|HSCR3

Gene name

glial cell derived neurotrophic factor

Gene Type

protein-coding

Chromosome

5

Genomics Location

5p13.1-p12

Known cancer genes

Yes

Protein products

Glial cell line-derived neurotrophic factor

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:4232
MIM:600837
Ensembl:ENSG00000168621
HPRD:02906
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

 

Ontology annotation

GO ID

GO annotation

GO:0001656

metanephros development

GO:0001657

ureteric bud development

GO:0001658

branching involved in ureteric bud morphogenesis

GO:0001755

neural crest cell migration

GO:0001759

organ induction

GO:0001941

postsynaptic membrane organization

GO:0005102

receptor binding

GO:0005576

extracellular region

GO:0006916

anti-apoptosis

GO:0007165

signal transduction

GO:0007399

nervous system development

GO:0007411

axon guidance

GO:0008083

growth factor activity

GO:0008344

adult locomotory behavior

GO:0021784

postganglionic parasympathetic nervous system development

GO:0030432

peristalsis

GO:0031175

neuron projection development

GO:0032770

positive regulation of monooxygenase activity

GO:0033603

positive regulation of dopamine secretion

GO:0042803

protein homodimerization activity

GO:0043524

negative regulation of neuron apoptosis

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048255

mRNA stabilization

GO:0048484

enteric nervous system development

GO:0048485

sympathetic nervous system development

GO:0051584

regulation of dopamine uptake

GO:0060688

regulation of morphogenesis of a branching structure

GO:0072107

positive regulation of ureteric bud formation

GO:0072108

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

GO:0090190

positive regulation of branching involved in ureteric bud morphogenesis