Gene basic information
| LiverAtlas Gene ID |
HuLG001802 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
GHR |
|
Synonyms |
GHBP |
|
Gene name |
growth hormone receptor |
|
Gene Type |
protein-coding |
|
Chromosome |
5 |
|
Genomics Location |
5p13-p12 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:4263
|
Liver relevance
| Liver sepcificity |
Yes/No |
Yes |
|
Evidence |
Translational level from literatures |
|
|
Quality score |
|
|
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0000255 |
allantoin metabolic process |
|
GO:0004872 |
receptor activity |
|
GO:0004903 |
growth hormone receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006101 |
citrate metabolic process |
|
GO:0006103 |
2-oxoglutarate metabolic process |
|
GO:0006105 |
succinate metabolic process |
|
GO:0006107 |
oxaloacetate metabolic process |
|
GO:0006549 |
isoleucine metabolic process |
|
GO:0006573 |
valine metabolic process |
|
GO:0006600 |
creatine metabolic process |
|
GO:0006631 |
fatty acid metabolic process |
|
GO:0006897 |
endocytosis |
|
GO:0007259 |
JAK-STAT cascade |
|
GO:0009755 |
hormone-mediated signaling pathway |
|
GO:0009986 |
cell surface |
|
GO:0016021 |
integral to membrane |
|
GO:0017046 |
peptide hormone binding |
|
GO:0019530 |
taurine metabolic process |
|
GO:0019838 |
growth factor binding |
|
GO:0019898 |
extrinsic to membrane |
|
GO:0019901 |
protein kinase binding |
|
GO:0019903 |
protein phosphatase binding |
|
GO:0031623 |
receptor internalization |
|
GO:0032094 |
response to food |
|
GO:0032355 |
response to estradiol stimulus |
|
GO:0032869 |
cellular response to insulin stimulus |
|
GO:0032870 |
cellular response to hormone stimulus |
|
GO:0040014 |
regulation of multicellular organism growth |
|
GO:0040018 |
positive regulation of multicellular organism growth |
|
GO:0042169 |
SH2 domain binding |
|
GO:0042517 |
positive regulation of tyrosine phosphorylation of Stat3 protein |
|
GO:0042523 |
positive regulation of tyrosine phosphorylation of Stat5 protein |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0042977 |
activation of JAK2 kinase activity |
|
GO:0043025 |
neuronal cell body |
|
GO:0043235 |
receptor complex |
|
GO:0043278 |
response to morphine |
|
GO:0043434 |
response to peptide hormone stimulus |
|
GO:0043526 |
neuroprotection |
|
GO:0044236 |
multicellular organismal metabolic process |
|
GO:0045597 |
positive regulation of cell differentiation |
|
GO:0046427 |
positive regulation of JAK-STAT cascade |
|
GO:0046449 |
creatinine metabolic process |
|
GO:0046898 |
response to cycloheximide |
|
GO:0048009 |
insulin-like growth factor receptor signaling pathway |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0051384 |
response to glucocorticoid stimulus |
|
GO:0060351 |
cartilage development involved in endochondral bone morphogenesis |
|
GO:0060396 |
growth hormone receptor signaling pathway |
|
GO:0070064 |
proline-rich region binding |
|
GO:0070195 |
growth hormone receptor complex |
|
GO:0070555 |
response to interleukin-1 |
