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Gene basic information

LiverAtlas Gene ID

HuLG001804

Entrez Gene ID

2692

Official Gene Symbol

GHRHR

Synonyms

GHRFR|GRFR|IGHD1B

Gene name

growth hormone releasing hormone receptor

Gene Type

protein-coding

Chromosome

7

Genomics Location

7p14

Known cancer genes

Yes

Protein products

Growth hormone-releasing hormone receptor

GHRH receptor splice variant 4

Database cross reference

HGNC:4266
MIM:139191
Ensembl:ENSG00000106128
HPRD:00748
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

 

Ontology annotation

GO ID

GO annotation

GO:0004930

G-protein coupled receptor activity

GO:0005515

protein binding

GO:0005624

membrane fraction

GO:0005637

nuclear inner membrane

GO:0005640

nuclear outer membrane

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007189

activation of adenylate cyclase activity by G-protein signaling pathway

GO:0007595

lactation

GO:0008284

positive regulation of cell proliferation

GO:0008340

determination of adult lifespan

GO:0009986

cell surface

GO:0016021

integral to membrane

GO:0016363

nuclear matrix

GO:0016520

growth hormone-releasing hormone receptor activity

GO:0017046

peptide hormone binding

GO:0019838

growth factor binding

GO:0019933

cAMP-mediated signaling

GO:0021984

adenohypophysis development

GO:0030104

water homeostasis

GO:0030141

stored secretory granule

GO:0030819

positive regulation of cAMP biosynthetic process

GO:0032868

response to insulin stimulus

GO:0032869

cellular response to insulin stimulus

GO:0033143

regulation of steroid hormone receptor signaling pathway

GO:0040018

positive regulation of multicellular organism growth

GO:0042445

hormone metabolic process

GO:0043568

positive regulation of insulin-like growth factor receptor signaling pathway

GO:0043627

response to estrogen stimulus

GO:0046887

positive regulation of hormone secretion

GO:0048469

cell maturation

GO:0048609

multicellular organismal reproductive process

GO:0051246

regulation of protein metabolic process

GO:0051384

response to glucocorticoid stimulus

GO:0060124

positive regulation of growth hormone secretion

GO:0060133

somatotropin secreting cell development