Gene basic information
| LiverAtlas Gene ID |
HuLG001809 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
GJA1 |
|
Synonyms |
CX43|DFNB38|GJAL|HSS|ODDD |
|
Gene name |
gap junction protein, alpha 1, 43kDa |
|
Gene Type |
protein-coding |
|
Chromosome |
6 |
|
Genomics Location |
6q21-q23.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:4274
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000139 |
Golgi membrane |
|
GO:0004871 |
signal transducer activity |
|
GO:0005243 |
gap junction channel activity |
|
GO:0005515 |
protein binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005741 |
mitochondrial outer membrane |
|
GO:0005764 |
lysosome |
|
GO:0005769 |
early endosome |
|
GO:0005771 |
multivesicular body |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0005916 |
fascia adherens |
|
GO:0005921 |
gap junction |
|
GO:0005922 |
connexon complex |
|
GO:0006810 |
transport |
|
GO:0006915 |
apoptosis |
|
GO:0006936 |
muscle contraction |
|
GO:0007165 |
signal transduction |
|
GO:0007267 |
cell-cell signaling |
|
GO:0007507 |
heart development |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009268 |
response to pH |
|
GO:0010232 |
vascular transport |
|
GO:0015075 |
ion transmembrane transporter activity |
|
GO:0015867 |
ATP transport |
|
GO:0016044 |
cellular membrane organization |
|
GO:0016264 |
gap junction assembly |
|
GO:0017124 |
SH3 domain binding |
|
GO:0022857 |
transmembrane transporter activity |
|
GO:0030054 |
cell junction |
|
GO:0030165 |
PDZ domain binding |
|
GO:0030660 |
Golgi-associated vesicle membrane |
|
GO:0034220 |
ion transmembrane transport |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043434 |
response to peptide hormone stimulus |
|
GO:0045121 |
membrane raft |
|
GO:0045732 |
positive regulation of protein catabolic process |
|
GO:0048812 |
neuron projection morphogenesis |
|
GO:0051259 |
protein oligomerization |
|
GO:0051924 |
regulation of calcium ion transport |
