Gene basic information
LiverAtlas Gene ID |
HuLG001828 |
Entrez Gene ID |
|
Official Gene Symbol |
GLI1 |
Synonyms |
GLI |
Gene name |
GLI family zinc finger 1 |
Gene Type |
protein-coding |
Chromosome |
12 |
Genomics Location |
12q13.2-q13.3 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:4317
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001649 |
osteoblast differentiation |
GO:0003677 |
DNA binding |
GO:0003682 |
chromatin binding |
GO:0003705 |
sequence-specific enhancer binding RNA polymerase II transcription factor activity |
GO:0005515 |
protein binding |
GO:0005622 |
intracellular |
GO:0005634 |
nucleus |
GO:0005737 |
cytoplasm |
GO:0005829 |
cytosol |
GO:0005929 |
cilium |
GO:0007275 |
multicellular organismal development |
GO:0007283 |
spermatogenesis |
GO:0007418 |
ventral midline development |
GO:0008017 |
microtubule binding |
GO:0008270 |
zinc ion binding |
GO:0008284 |
positive regulation of cell proliferation |
GO:0008589 |
regulation of smoothened signaling pathway |
GO:0009913 |
epidermal cell differentiation |
GO:0009953 |
dorsal/ventral pattern formation |
GO:0009954 |
proximal/distal pattern formation |
GO:0021696 |
cerebellar cortex morphogenesis |
GO:0021938 |
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation |
GO:0021983 |
pituitary gland development |
GO:0030324 |
lung development |
GO:0045740 |
positive regulation of DNA replication |
GO:0045880 |
positive regulation of smoothened signaling pathway |
GO:0045893 |
positive regulation of transcription, DNA-dependent |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046872 |
metal ion binding |
GO:0060032 |
notochord regression |
GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |