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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001828

Entrez Gene ID

2735

Official Gene Symbol

GLI1

Synonyms

GLI

Gene name

GLI family zinc finger 1

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q13.2-q13.3

Known cancer genes

Yes

Protein products

cDNA FLJ57539, highly similar to Zinc finger protein GLI1

Uncharacterized protein

Zinc finger protein GLI1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:4317
MIM:165220
Ensembl:ENSG00000111087
HPRD:01311
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001649

osteoblast differentiation

GO:0003677

DNA binding

GO:0003682

chromatin binding

GO:0003705

sequence-specific enhancer binding RNA polymerase II transcription factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005929

cilium

GO:0007275

multicellular organismal development

GO:0007283

spermatogenesis

GO:0007418

ventral midline development

GO:0008017

microtubule binding

GO:0008270

zinc ion binding

GO:0008284

positive regulation of cell proliferation

GO:0008589

regulation of smoothened signaling pathway

GO:0009913

epidermal cell differentiation

GO:0009953

dorsal/ventral pattern formation

GO:0009954

proximal/distal pattern formation

GO:0021696

cerebellar cortex morphogenesis

GO:0021938

smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation

GO:0021983

pituitary gland development

GO:0030324

lung development

GO:0045740

positive regulation of DNA replication

GO:0045880

positive regulation of smoothened signaling pathway

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046872

metal ion binding

GO:0060032

notochord regression

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway