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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001841

Entrez Gene ID

2752

Official Gene Symbol

GLUL

Synonyms

GLNS|GS|PIG43|PIG59

Gene name

glutamate-ammonia ligase

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q31

Protein products

Glutamine synthetase

Glutamine synthetase

Glutamine synthetase

Proliferation-inducing protein 43

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:4341
MIM:138290
Ensembl:ENSG00000135821
HPRD:00701
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001504

neurotransmitter uptake

GO:0004351

glutamate decarboxylase activity

GO:0004356

glutamate-ammonia ligase activity

GO:0005524

ATP binding

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0006542

glutamine biosynthetic process

GO:0007268

synaptic transmission

GO:0008283

cell proliferation

GO:0008652

cellular amino acid biosynthetic process

GO:0009749

response to glucose stimulus

GO:0016829

lyase activity

GO:0016874

ligase activity

GO:0034641

cellular nitrogen compound metabolic process

GO:0042802

identical protein binding