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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001850

Entrez Gene ID

2770

Official Gene Symbol

GNAI1

Synonyms

Gi

Gene name

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q21

Known cancer genes

Yes

Protein products

Guanine nucleotide-binding protein G(i) subunit alpha-1

Putative uncharacterized protein GNAI1

Related liver disease name

Hepatocellular carcinoma

Primary biliary cirrhosis

Database cross reference

HGNC:4384
MIM:139310
Ensembl:ENSG00000127955
HPRD:00756
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003924

GTPase activity

GO:0004871

signal transducer activity

GO:0005515

protein binding

GO:0005525

GTP binding

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0005813

centrosome

GO:0005834

heterotrimeric G-protein complex

GO:0005886

plasma membrane

GO:0006184

GTP catabolic process

GO:0007165

signal transduction

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007193

inhibition of adenylate cyclase activity by G-protein signaling pathway

GO:0007268

synaptic transmission

GO:0007596

blood coagulation

GO:0019001

guanyl nucleotide binding

GO:0030168

platelet activation

GO:0030496

midbody

GO:0031234

extrinsic to internal side of plasma membrane

GO:0031683

G-protein beta/gamma-subunit complex binding

GO:0031821

metabotropic serotonin receptor binding

GO:0051301

cell division