Gene basic information
| LiverAtlas Gene ID |
HuLG001858 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
GNAZ |
|
Gene name |
guanine nucleotide binding protein (G protein), alpha z polypeptide |
|
Gene Type |
protein-coding |
|
Chromosome |
22 |
|
Genomics Location |
22q11.22 |
|
Known cancer genes |
Yes |
|
Protein products |
Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide binding protein (G protein), alpha z polypeptide Guanine nucleotide binding protein (G protein), alpha z polypeptide |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:4395
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0003924 |
GTPase activity |
|
GO:0004871 |
signal transducer activity |
|
GO:0005057 |
receptor signaling protein activity |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005525 |
GTP binding |
|
GO:0005635 |
nuclear envelope |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005834 |
heterotrimeric G-protein complex |
|
GO:0005886 |
plasma membrane |
|
GO:0006184 |
GTP catabolic process |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0007188 |
G-protein signaling, coupled to cAMP nucleotide second messenger |
|
GO:0007193 |
inhibition of adenylate cyclase activity by G-protein signaling pathway |
|
GO:0019001 |
guanyl nucleotide binding |
|
GO:0031234 |
extrinsic to internal side of plasma membrane |
|
GO:0031683 |
G-protein beta/gamma-subunit complex binding |
|
GO:0031821 |
metabotropic serotonin receptor binding |
