Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001881

Entrez Gene ID

2806

Official Gene Symbol

GOT2

Synonyms

FLJ40994|KAT4|KATIV|mitAAT

Gene name

glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

Gene Type

protein-coding

Chromosome

16

Genomics Location

16q21

Known cancer genes

Yes

Protein products

Aspartate aminotransferase, mitochondrial

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:4433
MIM:138150
Ensembl:ENSG00000125166
HPRD:00684
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005743

mitochondrial inner membrane

GO:0005759

mitochondrial matrix

GO:0005886

plasma membrane

GO:0005975

carbohydrate metabolic process

GO:0006006

glucose metabolic process

GO:0006094

gluconeogenesis

GO:0006103

2-oxoglutarate metabolic process

GO:0006107

oxaloacetate metabolic process

GO:0006531

aspartate metabolic process

GO:0006532

aspartate biosynthetic process

GO:0006533

aspartate catabolic process

GO:0006536

glutamate metabolic process

GO:0006810

transport

GO:0008652

cellular amino acid biosynthetic process

GO:0009058

biosynthetic process

GO:0015908

fatty acid transport

GO:0019550

glutamate catabolic process to aspartate

GO:0019551

glutamate catabolic process to 2-oxoglutarate

GO:0030170

pyridoxal phosphate binding

GO:0034641

cellular nitrogen compound metabolic process

GO:0045471

response to ethanol