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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001934

Entrez Gene ID

2875

Official Gene Symbol

GPT

Synonyms

AAT1|ALT1|GPT1

Gene name

glutamic-pyruvate transaminase (alanine aminotransferase)

Gene Type

protein-coding

Chromosome

8

Genomics Location

8q24.3

Known cancer genes

Yes

Protein products

Alanine aminotransferase 1

Related liver disease name

Hepatocellular carcinoma

Hepatitis D

Autoimmune hepatitis

Schistosomiasis

Database cross reference

HGNC:4552
MIM:138200
Ensembl:ENSG00000167701
HPRD:00689
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004021

L-alanine:2-oxoglutarate aminotransferase activity

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006094

gluconeogenesis

GO:0006807

nitrogen compound metabolic process

GO:0008483

transaminase activity

GO:0008652

cellular amino acid biosynthetic process

GO:0009058

biosynthetic process

GO:0016847

1-aminocyclopropane-1-carboxylate synthase activity

GO:0030170

pyridoxal phosphate binding

GO:0034641

cellular nitrogen compound metabolic process