Gene basic information
| LiverAtlas Gene ID |
HuLG001935 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
GPX1 |
|
Synonyms |
GSHPX1|MGC14399|MGC88245 |
|
Gene name |
glutathione peroxidase 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p21.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:4553
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001836 |
release of cytochrome c from mitochondria |
|
GO:0004602 |
glutathione peroxidase activity |
|
GO:0004866 |
endopeptidase inhibitor activity |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005829 |
cytosol |
|
GO:0006144 |
purine base metabolic process |
|
GO:0006195 |
purine nucleotide catabolic process |
|
GO:0006749 |
glutathione metabolic process |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006979 |
response to oxidative stress |
|
GO:0009650 |
UV protection |
|
GO:0010269 |
response to selenium ion |
|
GO:0010951 |
negative regulation of endopeptidase activity |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0017124 |
SH3 domain binding |
|
GO:0033599 |
regulation of mammary gland epithelial cell proliferation |
|
GO:0040029 |
regulation of gene expression, epigenetic |
|
GO:0042542 |
response to hydrogen peroxide |
|
GO:0042744 |
hydrogen peroxide catabolic process |
|
GO:0043154 |
negative regulation of caspase activity |
|
GO:0045454 |
cell redox homeostasis |
|
GO:0055086 |
nucleobase, nucleoside and nucleotide metabolic process |
|
GO:0060047 |
heart contraction |
|
GO:0061136 |
regulation of proteasomal protein catabolic process |
