HuLG001960

Entrez Gene ID

2904

Official Gene Symbol

GRIN2B

Synonyms

MGC142178|MGC142180|NMDAR2B|NR2B|hNR3

Gene name

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p12

Known cancer genes

Yes

Protein products

Glutamate [NMDA] receptor subunit epsilon-2

Related liver disease name

Alcoholic liver cirrhosis

Database cross reference

HGNC:4586
MIM:138252
Ensembl:ENSG00000150086
HPRD:00697
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

GO annotation

GO:0001101

response to acid

GO:0001508

regulation of action potential

GO:0001662

behavioral fear response

GO:0001701

in utero embryonic development

GO:0001964

startle response

GO:0001967

suckling behavior

GO:0001975

response to amphetamine

GO:0004872

receptor activity

GO:0004972

N-methyl-D-aspartate selective glutamate receptor activity

GO:0005102

receptor binding

GO:0005215

transporter activity

GO:0005234

extracellular-glutamate-gated ion channel activity

GO:0005262

calcium channel activity

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006810

transport

GO:0006812

cation transport

GO:0007215

glutamate signaling pathway

GO:0007268

synaptic transmission

GO:0007423

sensory organ development

GO:0007611

learning or memory

GO:0007616

long-term memory

GO:0008013

beta-catenin binding

GO:0008021

synaptic vesicle

GO:0008144

drug binding

GO:0008270

zinc ion binding

GO:0008306

associative learning

GO:0009612

response to mechanical stimulus

GO:0009743

response to carbohydrate stimulus

GO:0009790

embryo development

GO:0010350

cellular response to magnesium starvation

GO:0010942

positive regulation of cell death

GO:0014049

positive regulation of glutamate secretion

GO:0014069

postsynaptic density

GO:0016594

glycine binding

GO:0016600

flotillin complex

GO:0017146

N-methyl-D-aspartate selective glutamate receptor complex

GO:0019717

synaptosome

GO:0021766

hippocampus development

GO:0021987

cerebral cortex development

GO:0030018

Z disc

GO:0030054

cell junction

GO:0030288

outer membrane-bounded periplasmic space

GO:0031749

D2 dopamine receptor binding

GO:0032026

response to magnesium ion

GO:0034097

response to cytokine stimulus

GO:0035235

ionotropic glutamate receptor signaling pathway

GO:0035255

ionotropic glutamate receptor binding

GO:0042165

neurotransmitter binding

GO:0042220

response to cocaine

GO:0042734

presynaptic membrane

GO:0043005

neuron projection

GO:0043083

synaptic cleft

GO:0043113

receptor clustering

GO:0043195

terminal button

GO:0043197

dendritic spine

GO:0043408

regulation of MAPKKK cascade

GO:0045202

synapse

GO:0045211

postsynaptic membrane

GO:0045471

response to ethanol

GO:0046872

metal ion binding

GO:0046982

protein heterodimerization activity

GO:0048167

regulation of synaptic plasticity

GO:0048169

regulation of long-term neuronal synaptic plasticity

GO:0048266

behavioral response to pain

GO:0048511

rhythmic process

GO:0050806

positive regulation of synaptic transmission

GO:0050839

cell adhesion molecule binding

GO:0050966

detection of mechanical stimulus involved in sensory perception of pain

GO:0051592

response to calcium ion

GO:0051597

response to methylmercury

GO:0051602

response to electrical stimulus

GO:0051707

response to other organism

GO:0060079

regulation of excitatory postsynaptic membrane potential

GO:0060416

response to growth hormone stimulus

GO:0060992

response to fungicide

GO:0071230

cellular response to amino acid stimulus

GO:0071287

cellular response to manganese ion

GO:0071359

cellular response to dsRNA

GO:0071363

cellular response to growth factor stimulus

GO:0071396

cellular response to lipid

GO:0071407

cellular response to organic cyclic compound

GO:0071445

cellular response to protein stimulus