Gene basic information
| LiverAtlas Gene ID |
HuLG001964 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
NR3C1 |
|
Synonyms |
GCCR|GCR|GR|GRL |
|
Gene name |
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
|
Gene Type |
protein-coding |
|
Chromosome |
5 |
|
Genomics Location |
5q31.3 |
|
Known cancer genes |
Yes |
|
Protein products |
Glucocorticoid nuclear receptor variant 1 Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor) Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:7978
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0004883 |
glucocorticoid receptor activity |
|
GO:0005496 |
steroid binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005759 |
mitochondrial matrix |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006366 |
transcription from RNA polymerase II promoter |
|
GO:0007165 |
signal transduction |
|
GO:0008270 |
zinc ion binding |
|
GO:0010467 |
gene expression |
|
GO:0016568 |
chromatin modification |
|
GO:0034339 |
regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor |
|
GO:0042921 |
glucocorticoid receptor signaling pathway |
|
GO:0043402 |
glucocorticoid mediated signaling pathway |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0046872 |
metal ion binding |
|
GO:0051789 |
response to protein stimulus |
