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Gene basic information

LiverAtlas Gene ID

HuLG001987

Entrez Gene ID

2937

Official Gene Symbol

GSS

Synonyms

GSHS|MGC14098

Gene name

glutathione synthetase

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q11.2

Known cancer genes

Yes

Protein products

Glutathione synthetase

Related liver disease name

Alcoholic liver disease

Database cross reference

HGNC:4624
MIM:601002
Ensembl:ENSG00000100983
HPRD:03000
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000287

magnesium ion binding

GO:0004363

glutathione synthase activity

GO:0005524

ATP binding

GO:0005625

soluble fraction

GO:0005829

cytosol

GO:0006520

cellular amino acid metabolic process

GO:0006750

glutathione biosynthetic process

GO:0006805

xenobiotic metabolic process

GO:0006979

response to oxidative stress

GO:0007399

nervous system development

GO:0007568

aging

GO:0009410

response to xenobiotic stimulus

GO:0016594

glycine binding

GO:0016874

ligase activity

GO:0031667

response to nutrient levels

GO:0034612

response to tumor necrosis factor

GO:0042803

protein homodimerization activity

GO:0043200

response to amino acid stimulus

GO:0043295

glutathione binding

GO:0046686

response to cadmium ion