Gene basic information
| LiverAtlas Gene ID |
HuLG001996 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
GSTP1 |
|
Synonyms |
DFN7|FAEES3|GST3|GSTP|PI |
|
Gene name |
glutathione S-transferase pi 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q13 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection |
|
Database cross reference |
HGNC:4638
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000302 |
response to reactive oxygen species |
|
GO:0002674 |
negative regulation of acute inflammatory response |
|
GO:0004364 |
glutathione transferase activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006469 |
negative regulation of protein kinase activity |
|
GO:0006749 |
glutathione metabolic process |
|
GO:0006805 |
xenobiotic metabolic process |
|
GO:0006916 |
anti-apoptosis |
|
GO:0007417 |
central nervous system development |
|
GO:0008152 |
metabolic process |
|
GO:0008432 |
JUN kinase binding |
|
GO:0009890 |
negative regulation of biosynthetic process |
|
GO:0010804 |
negative regulation of tumor necrosis factor-mediated signaling pathway |
|
GO:0016740 |
transferase activity |
|
GO:0019207 |
kinase regulator activity |
|
GO:0032691 |
negative regulation of interleukin-1 beta production |
|
GO:0032720 |
negative regulation of tumor necrosis factor production |
|
GO:0032872 |
regulation of stress-activated MAPK cascade |
|
GO:0032873 |
negative regulation of stress-activated MAPK cascade |
|
GO:0032930 |
positive regulation of superoxide anion generation |
|
GO:0035726 |
common myeloid progenitor cell proliferation |
|
GO:0035730 |
S-nitrosoglutathione binding |
|
GO:0035731 |
dinitrosyl-iron complex binding |
|
GO:0035732 |
nitric oxide storage |
|
GO:0042325 |
regulation of phosphorylation |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043124 |
negative regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043234 |
protein complex |
|
GO:0043407 |
negative regulation of MAP kinase activity |
|
GO:0043409 |
negative regulation of MAPKKK cascade |
|
GO:0043508 |
negative regulation of JUN kinase activity |
|
GO:0048147 |
negative regulation of fibroblast proliferation |
|
GO:0051774 |
negative regulation of nitric-oxide synthase 2 biosynthetic process |
|
GO:0060547 |
negative regulation of necrotic cell death |
|
GO:0070026 |
nitric oxide binding |
|
GO:0070372 |
regulation of ERK1 and ERK2 cascade |
|
GO:0070373 |
negative regulation of ERK1 and ERK2 cascade |
|
GO:0070664 |
negative regulation of leukocyte proliferation |
|
GO:0071222 |
cellular response to lipopolysaccharide |
|
GO:0071638 |
negative regulation of monocyte chemotactic protein-1 production |
