Gene basic information
| LiverAtlas Gene ID |
HuLG002089 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
HDAC1 |
|
Synonyms |
DKFZp686H12203|GONN10|HD1|RPD3|RPD3L1 |
|
Gene name |
histone deacetylase 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p34 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:4852
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000118 |
histone deacetylase complex |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0001106 |
RNA polymerase II transcription corepressor activity |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0004407 |
histone deacetylase activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006338 |
chromatin remodeling |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006476 |
protein deacetylation |
|
GO:0006916 |
anti-apoptosis |
|
GO:0007596 |
blood coagulation |
|
GO:0008134 |
transcription factor binding |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0009913 |
epidermal cell differentiation |
|
GO:0010832 |
negative regulation of myotube differentiation |
|
GO:0010870 |
positive regulation of receptor biosynthetic process |
|
GO:0016568 |
chromatin modification |
|
GO:0016575 |
histone deacetylation |
|
GO:0016580 |
Sin3 complex |
|
GO:0016581 |
NuRD complex |
|
GO:0016787 |
hydrolase activity |
|
GO:0019899 |
enzyme binding |
|
GO:0032041 |
NAD-dependent histone deacetylase activity (H3-K14 specific) |
|
GO:0033558 |
protein deacetylase activity |
|
GO:0033613 |
activating transcription factor binding |
|
GO:0034739 |
histone deacetylase activity (H3-K16 specific) |
|
GO:0042475 |
odontogenesis of dentine-containing tooth |
|
GO:0042733 |
embryonic digit morphogenesis |
|
GO:0042802 |
identical protein binding |
|
GO:0042826 |
histone deacetylase binding |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043922 |
negative regulation by host of viral transcription |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045786 |
negative regulation of cell cycle |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046969 |
NAD-dependent histone deacetylase activity (H3-K9 specific) |
|
GO:0046970 |
NAD-dependent histone deacetylase activity (H4-K16 specific) |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0060766 |
negative regulation of androgen receptor signaling pathway |
|
GO:0060789 |
hair follicle placode formation |
|
GO:0061029 |
eyelid development in camera-type eye |
|
GO:0061198 |
fungiform papilla formation |
|
GO:0070932 |
histone H3 deacetylation |
|
GO:0070933 |
histone H4 deacetylation |
