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Gene basic information

LiverAtlas Gene ID

HuLG002090

Entrez Gene ID

3066

Official Gene Symbol

HDAC2

Synonyms

HD2|RPD3|YAF1

Gene name

histone deacetylase 2

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q21

Known cancer genes

Yes

Protein products

Histone deacetylase 2

Database cross reference

HGNC:4853
MIM:605164
Ensembl:ENSG00000196591
HPRD:05521
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0000790

nuclear chromatin

GO:0000792

heterochromatin

GO:0003682

chromatin binding

GO:0004407

histone deacetylase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005657

replication fork

GO:0005667

transcription factor complex

GO:0005737

cytoplasm

GO:0006338

chromatin remodeling

GO:0006344

maintenance of chromatin silencing

GO:0007596

blood coagulation

GO:0008134

transcription factor binding

GO:0008284

positive regulation of cell proliferation

GO:0009913

epidermal cell differentiation

GO:0010870

positive regulation of receptor biosynthetic process

GO:0010977

negative regulation of neuron projection development

GO:0016358

dendrite development

GO:0016575

histone deacetylation

GO:0016580

Sin3 complex

GO:0016581

NuRD complex

GO:0016787

hydrolase activity

GO:0019899

enzyme binding

GO:0021766

hippocampus development

GO:0030182

neuron differentiation

GO:0031072

heat shock protein binding

GO:0032041

NAD-dependent histone deacetylase activity (H3-K14 specific)

GO:0033558

protein deacetylase activity

GO:0034605

cellular response to heat

GO:0034739

histone deacetylase activity (H3-K16 specific)

GO:0035098

ESC/E(Z) complex

GO:0042220

response to cocaine

GO:0042475

odontogenesis of dentine-containing tooth

GO:0042493

response to drug

GO:0042733

embryonic digit morphogenesis

GO:0043066

negative regulation of apoptosis

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

GO:0043565

sequence-specific DNA binding

GO:0045786

negative regulation of cell cycle

GO:0045862

positive regulation of proteolysis

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046969

NAD-dependent histone deacetylase activity (H3-K9 specific)

GO:0046970

NAD-dependent histone deacetylase activity (H4-K16 specific)

GO:0048011

nerve growth factor receptor signaling pathway

GO:0060789

hair follicle placode formation

GO:0061029

eyelid development in camera-type eye

GO:0061198

fungiform papilla formation