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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002094

Entrez Gene ID

3070

Official Gene Symbol

HELLS

Synonyms

FLJ10339|LSH|PASG|SMARCA6

Gene name

helicase, lymphoid-specific

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q24.2

Known cancer genes

Yes

Protein products

Lymphoid-specific helicase

Lymphoid specific helicase variant9

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatitis C

Chronic hepatitis C

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:4861
MIM:603946
Ensembl:ENSG00000119969
HPRD:07232
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000775

chromosome, centromeric region

GO:0001655

urogenital system development

GO:0003677

DNA binding

GO:0003682

chromatin binding

GO:0004386

helicase activity

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005721

centromeric heterochromatin

GO:0006346

methylation-dependent chromatin silencing

GO:0006355

regulation of transcription, DNA-dependent

GO:0006916

anti-apoptosis

GO:0007049

cell cycle

GO:0007067

mitosis

GO:0007275

multicellular organismal development

GO:0010216

maintenance of DNA methylation

GO:0016787

hydrolase activity

GO:0031508

centromeric heterochromatin formation

GO:0046651

lymphocyte proliferation

GO:0051301

cell division