Gene basic information
| LiverAtlas Gene ID |
HuLG002099 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
HFE |
|
Synonyms |
HFE1|HH|HLANH|MGC103790|MVCD7|dJ221C16.10.1 |
|
Gene name |
hemochromatosis |
|
Gene Type |
protein-coding |
|
Chromosome |
6 |
|
Genomics Location |
6p21.3 |
|
Known cancer genes |
Yes |
|
Protein products |
Hereditary hemochromatosis protein Hereditary hemochromatosis protein HLA-H |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:4886
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002474 |
antigen processing and presentation of peptide antigen via MHC class I |
|
GO:0005515 |
protein binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005769 |
early endosome |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006461 |
protein complex assembly |
|
GO:0006811 |
ion transport |
|
GO:0006826 |
iron ion transport |
|
GO:0006879 |
cellular iron ion homeostasis |
|
GO:0006898 |
receptor-mediated endocytosis |
|
GO:0006955 |
immune response |
|
GO:0007565 |
female pregnancy |
|
GO:0010106 |
cellular response to iron ion starvation |
|
GO:0019882 |
antigen processing and presentation |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0042446 |
hormone biosynthetic process |
|
GO:0042612 |
MHC class I protein complex |
|
GO:0045177 |
apical part of cell |
|
GO:0045178 |
basal part of cell |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0055037 |
recycling endosome |
|
GO:0060586 |
multicellular organismal iron ion homeostasis |
