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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002103

Entrez Gene ID

3082

Official Gene Symbol

HGF

Synonyms

DFNB39|FNTCF|HGFB|HPTA|SF

Gene name

hepatocyte growth factor (hepapoietin A; scatter factor)

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q21.1

Known cancer genes

Yes

Protein products

Hepatocyte growth factor

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Chronic hepatitis

Alcoholic hepatitis

Drug-induced hepatitis

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:4893
MIM:142409
Ensembl:ENSG00000019991
HPRD:00799
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000187

activation of MAPK activity

GO:0000902

cell morphogenesis

GO:0001837

epithelial to mesenchymal transition

GO:0001889

liver development

GO:0002576

platelet degranulation

GO:0003824

catalytic activity

GO:0004252

serine-type endopeptidase activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006508

proteolysis

GO:0006916

anti-apoptosis

GO:0007067

mitosis

GO:0007596

blood coagulation

GO:0008083

growth factor activity

GO:0030168

platelet activation

GO:0031093

platelet alpha granule lumen

GO:0031100

organ regeneration

GO:0046982

protein heterodimerization activity

GO:0048012

hepatocyte growth factor receptor signaling pathway

GO:0051450

myoblast proliferation

GO:0060665

regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling