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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002130

Entrez Gene ID

3119

Official Gene Symbol

HLA-DQB1

Synonyms

CELIAC1|HLANDQB|IDDM1

Gene name

major histocompatibility complex, class II, DQ beta 1

Gene Type

protein-coding

Chromosome

6

Genomics Location

6p21.3

Protein products

HLA-DQB1 protein

HLA class II histocompatibility antigen, DQ beta 1 chain

HLA-DQB1 protein

Major histocompatibility complex, class II, DQ beta 1

MHC class II antigen

MHC class II antigen

MHC class II antigen

MHC class II antigen

MHC class II antigen

MHC class II antigen

MHC class II antigen

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Drug-induced hepatitis

Biliary cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Autoimmune hepatitis

Database cross reference

HGNC:4944
MIM:604305
Ensembl:ENSG00000179344
HPRD:05054
RefSeq Genomic nucleotide accession:NC_000006
RefSeq Genomic nucleotide gi:224589818

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002504

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

GO:0005765

lysosomal membrane

GO:0005768

endosome

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0006955

immune response

GO:0010008

endosome membrane

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0019221

cytokine-mediated signaling pathway

GO:0031295

T cell costimulation

GO:0032395

MHC class II receptor activity

GO:0042613

MHC class II protein complex

GO:0050852

T cell receptor signaling pathway

GO:0060333

interferon-gamma-mediated signaling pathway