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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002131

Entrez Gene ID

3122

Official Gene Symbol

HLA-DRA

Synonyms

FLJ51114|HLANDRA1|MLRW

Gene name

major histocompatibility complex, class II, DR alpha

Gene Type

protein-coding

Chromosome

6

Genomics Location

6p21.3

Protein products

MHC class II antigen

HLA class II histocompatibility antigen, DR alpha chain

MHC class II antigen

MHC cell surface glycoprotein

MHC class II antigen DRB5*01012

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:4947
MIM:142860
Ensembl:ENSG00000204287
HPRD:00833
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002504

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

GO:0005764

lysosome

GO:0005765

lysosomal membrane

GO:0005768

endosome

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006955

immune response

GO:0019221

cytokine-mediated signaling pathway

GO:0031295

T cell costimulation

GO:0031902

late endosome membrane

GO:0032395

MHC class II receptor activity

GO:0042613

MHC class II protein complex

GO:0050852

T cell receptor signaling pathway

GO:0060333

interferon-gamma-mediated signaling pathway