Gene basic information
LiverAtlas Gene ID |
HuLG002132 |
Entrez Gene ID |
|
Official Gene Symbol |
HLA-DRB1 |
Synonyms |
DRB1|DRw10|FLJ75017|FLJ76359|HLANDR1B|HLANDRB|SS1 |
Gene name |
major histocompatibility complex, class II, DR beta 1 |
Gene Type |
protein-coding |
Chromosome |
6 |
Genomics Location |
6p21.3 |
Protein products |
HLA class II histocompatibility antigen, DRB1-1 beta chain HLA class II histocompatibility antigen, DRB1-8 beta chain HLA class II histocompatibility antigen, DRB1-15 beta chain MHC HLA-DR-beta cell surface glycoprotein MHC HLA-DR-beta cell surface glycoprotein MHC HLA-DR-beta cell surface glycoprotein MHC HLA-DR-beta cell surface glycoprotein |
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
Database cross reference |
HGNC:4948
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0002504 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
GO:0005765 |
lysosomal membrane |
GO:0005768 |
endosome |
GO:0005783 |
endoplasmic reticulum |
GO:0005789 |
endoplasmic reticulum membrane |
GO:0005794 |
Golgi apparatus |
GO:0005886 |
plasma membrane |
GO:0005887 |
integral to plasma membrane |
GO:0006955 |
immune response |
GO:0016020 |
membrane |
GO:0016021 |
integral to membrane |
GO:0019221 |
cytokine-mediated signaling pathway |
GO:0031295 |
T cell costimulation |
GO:0031902 |
late endosome membrane |
GO:0032395 |
MHC class II receptor activity |
GO:0042613 |
MHC class II protein complex |
GO:0050852 |
T cell receptor signaling pathway |
GO:0060333 |
interferon-gamma-mediated signaling pathway |