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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002134

Entrez Gene ID

3126

Official Gene Symbol

HLA-DRB4

Synonyms

DRB4|HLANDR4B

Gene name

major histocompatibility complex, class II, DR beta 4

Gene Type

protein-coding

Chromosome

6

Genomics Location

6p21.3

Protein products

HLA class II histocompatibility antigen, DR beta 4 chain

HLA-DRB4 protein

MHC class II antigen

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Hepatocellular carcinoma

Autoimmune hepatitis

Primary sclerosing cholangitis

Database cross reference

HGNC:4952
HPRD:09986
RefSeq Genomic nucleotide accession:NG_002433
RefSeq Genomic nucleotide gi:28212470



Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002504

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

GO:0005765

lysosomal membrane

GO:0005768

endosome

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006955

immune response

GO:0007165

signal transduction

GO:0016021

integral to membrane

GO:0019221

cytokine-mediated signaling pathway

GO:0031295

T cell costimulation

GO:0031902

late endosome membrane

GO:0032395

MHC class II receptor activity

GO:0042613

MHC class II protein complex

GO:0050852

T cell receptor signaling pathway

GO:0060333

interferon-gamma-mediated signaling pathway