Gene basic information
| LiverAtlas Gene ID |
HuLG002148 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
HMGB2 |
|
Synonyms |
HMG2 |
|
Gene name |
high mobility group box 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
4 |
|
Genomics Location |
4q31 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:5000
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000793 |
condensed chromosome |
|
GO:0001938 |
positive regulation of endothelial cell proliferation |
|
GO:0003677 |
DNA binding |
|
GO:0003684 |
damaged DNA binding |
|
GO:0003690 |
double-stranded DNA binding |
|
GO:0003697 |
single-stranded DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0005515 |
protein binding |
|
GO:0005615 |
extracellular space |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0006265 |
DNA topological change |
|
GO:0006288 |
base-excision repair, DNA ligation |
|
GO:0006309 |
DNA fragmentation involved in apoptotic nuclear change |
|
GO:0006325 |
chromatin organization |
|
GO:0006334 |
nucleosome assembly |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
|
GO:0006915 |
apoptosis |
|
GO:0006921 |
cellular component disassembly involved in apoptosis |
|
GO:0007283 |
spermatogenesis |
|
GO:0007289 |
spermatid nucleus differentiation |
|
GO:0008301 |
DNA bending activity |
|
GO:0008584 |
male gonad development |
|
GO:0019904 |
protein domain specific binding |
|
GO:0032075 |
positive regulation of nuclease activity |
|
GO:0033151 |
V(D)J recombination |
|
GO:0042056 |
chemoattractant activity |
|
GO:0043234 |
protein complex |
|
GO:0043388 |
positive regulation of DNA binding |
|
GO:0045648 |
positive regulation of erythrocyte differentiation |
|
GO:0045654 |
positive regulation of megakaryocyte differentiation |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0048015 |
phosphatidylinositol-mediated signaling |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0048545 |
response to steroid hormone stimulus |
|
GO:0050786 |
RAGE receptor binding |
|
GO:0050918 |
positive chemotaxis |
|
GO:0051103 |
DNA ligation involved in DNA repair |
|
GO:0060326 |
cell chemotaxis |
|
GO:0071222 |
cellular response to lipopolysaccharide |
