Gene basic information
| LiverAtlas Gene ID |
HuLG002155 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
HMGCS2 |
|
Gene name |
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p13-p12 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ56838, highly similar to Hydroxymethylglutaryl-CoA synthase, mitochondrial (EC 2.3.3.10) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:5008
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001822 |
kidney development |
|
GO:0001889 |
liver development |
|
GO:0004421 |
hydroxymethylglutaryl-CoA synthase activity |
|
GO:0005739 |
mitochondrion |
|
GO:0005759 |
mitochondrial matrix |
|
GO:0006695 |
cholesterol biosynthetic process |
|
GO:0007420 |
brain development |
|
GO:0007494 |
midgut development |
|
GO:0007584 |
response to nutrient |
|
GO:0008299 |
isoprenoid biosynthetic process |
|
GO:0009266 |
response to temperature stimulus |
|
GO:0009617 |
response to bacterium |
|
GO:0010038 |
response to metal ion |
|
GO:0016740 |
transferase activity |
|
GO:0030324 |
lung development |
|
GO:0032869 |
cellular response to insulin stimulus |
|
GO:0032870 |
cellular response to hormone stimulus |
|
GO:0033555 |
multicellular organismal response to stress |
|
GO:0033574 |
response to testosterone stimulus |
|
GO:0033762 |
response to glucagon stimulus |
|
GO:0034014 |
response to triglyceride |
|
GO:0034284 |
response to monosaccharide stimulus |
|
GO:0034696 |
response to prostaglandin F stimulus |
|
GO:0042493 |
response to drug |
|
GO:0042594 |
response to starvation |
|
GO:0043441 |
acetoacetic acid biosynthetic process |
|
GO:0044255 |
cellular lipid metabolic process |
|
GO:0045471 |
response to ethanol |
|
GO:0046950 |
cellular ketone body metabolic process |
|
GO:0046951 |
ketone body biosynthetic process |
|
GO:0051591 |
response to cAMP |
|
GO:0060416 |
response to growth hormone stimulus |
|
GO:0060612 |
adipose tissue development |
|
GO:0070543 |
response to linoleic acid |
|
GO:0071222 |
cellular response to lipopolysaccharide |
|
GO:0071230 |
cellular response to amino acid stimulus |
|
GO:0071385 |
cellular response to glucocorticoid stimulus |
|
GO:0071398 |
cellular response to fatty acid |
|
GO:0071407 |
cellular response to organic cyclic compound |
|
GO:0071445 |
cellular response to protein stimulus |
