Gene basic information
| LiverAtlas Gene ID |
HuLG002159 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
HMOX1 |
|
Synonyms |
HON1|HSP32|bK286B10 |
|
Gene name |
heme oxygenase (decycling) 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
22 |
|
Genomics Location |
22q12|22q13.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis |
|
Database cross reference |
HGNC:5013
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001525 |
angiogenesis |
|
GO:0001666 |
response to hypoxia |
|
GO:0001935 |
endothelial cell proliferation |
|
GO:0002246 |
wound healing involved in inflammatory response |
|
GO:0002686 |
negative regulation of leukocyte migration |
|
GO:0004392 |
heme oxygenase (decyclizing) activity |
|
GO:0004630 |
phospholipase D activity |
|
GO:0004871 |
signal transducer activity |
|
GO:0005615 |
extracellular space |
|
GO:0005624 |
membrane fraction |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005792 |
microsome |
|
GO:0005829 |
cytosol |
|
GO:0005901 |
caveola |
|
GO:0006778 |
porphyrin metabolic process |
|
GO:0006788 |
heme oxidation |
|
GO:0006879 |
cellular iron ion homeostasis |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006979 |
response to oxidative stress |
|
GO:0007165 |
signal transduction |
|
GO:0007243 |
intracellular protein kinase cascade |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0007588 |
excretion |
|
GO:0008217 |
regulation of blood pressure |
|
GO:0008219 |
cell death |
|
GO:0008630 |
DNA damage response, signal transduction resulting in induction of apoptosis |
|
GO:0014806 |
smooth muscle hyperplasia |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0019899 |
enzyme binding |
|
GO:0020037 |
heme binding |
|
GO:0031670 |
cellular response to nutrient |
|
GO:0032764 |
negative regulation of mast cell cytokine production |
|
GO:0034101 |
erythrocyte homeostasis |
|
GO:0034383 |
low-density lipoprotein particle clearance |
|
GO:0035094 |
response to nicotine |
|
GO:0042167 |
heme catabolic process |
|
GO:0042542 |
response to hydrogen peroxide |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043305 |
negative regulation of mast cell degranulation |
|
GO:0043392 |
negative regulation of DNA binding |
|
GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0043619 |
regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
|
GO:0043627 |
response to estrogen stimulus |
|
GO:0045080 |
positive regulation of chemokine biosynthetic process |
|
GO:0045765 |
regulation of angiogenesis |
|
GO:0045766 |
positive regulation of angiogenesis |
|
GO:0045768 |
positive regulation of anti-apoptosis |
|
GO:0045909 |
positive regulation of vasodilation |
|
GO:0046872 |
metal ion binding |
|
GO:0048661 |
positive regulation of smooth muscle cell proliferation |
|
GO:0048662 |
negative regulation of smooth muscle cell proliferation |
|
GO:0050896 |
response to stimulus |
|
GO:0051090 |
regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0051260 |
protein homooligomerization |
|
GO:0055072 |
iron ion homeostasis |
|
GO:0055085 |
transmembrane transport |
