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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002226

Entrez Gene ID

3242

Official Gene Symbol

HPD

Synonyms

4NHPPD|4HPPD|GLOD3|HPPDASE|PPD

Gene name

4-hydroxyphenylpyruvate dioxygenase

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24-qter

Protein products

cDNA FLJ32948 fis, clone TESTI2008014, highly similar to 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)

4-hydroxyphenylpyruvate dioxygenase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:5147
MIM:609695
Ensembl:ENSG00000158104
HPRD:02041
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000139

Golgi membrane

GO:0003868

4-hydroxyphenylpyruvate dioxygenase activity

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0006559

L-phenylalanine catabolic process

GO:0006572

tyrosine catabolic process

GO:0009072

aromatic amino acid family metabolic process

GO:0016491

oxidoreductase activity

GO:0034641

cellular nitrogen compound metabolic process

GO:0046872

metal ion binding