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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002234

Entrez Gene ID

3265

Official Gene Symbol

HRAS

Synonyms

CNBAS/HAS|CNHNRAS|CNHANRAS1|CTLO|HNRASIDX|HAMSV|HRAS1|KNRAS|NNRAS|RASH1

Gene name

v-Ha-ras Harvey rat sarcoma viral oncogene homolog

Gene Type

protein-coding

Chromosome

11

Genomics Location

11p15.5

Known cancer genes

Yes

Protein products

V-Ha-ras Harvey rat sarcoma viral oncogene homolog

GTPase HRas

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatitis B

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Primary sclerosing cholangitis

Database cross reference

HGNC:5173
MIM:190020
Ensembl:ENSG00000174775
HPRD:01813
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000139

Golgi membrane

GO:0000165

MAPKKK cascade

GO:0000166

nucleotide binding

GO:0000186

activation of MAPKK activity

GO:0003924

GTPase activity

GO:0005515

protein binding

GO:0005525

GTP binding

GO:0005622

intracellular

GO:0005625

soluble fraction

GO:0005737

cytoplasm

GO:0005792

microsome

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006915

apoptosis

GO:0006935

chemotaxis

GO:0007050

cell cycle arrest

GO:0007165

signal transduction

GO:0007166

cell surface receptor linked signaling pathway

GO:0007173

epidermal growth factor receptor signaling pathway

GO:0007264

small GTPase mediated signal transduction

GO:0007265

Ras protein signal transduction

GO:0007268

synaptic transmission

GO:0007411

axon guidance

GO:0007596

blood coagulation

GO:0008022

protein C-terminus binding

GO:0008284

positive regulation of cell proliferation

GO:0008285

negative regulation of cell proliferation

GO:0008286

insulin receptor signaling pathway

GO:0009887

organ morphogenesis

GO:0031575

mitotic cell cycle G1/S transition checkpoint

GO:0035176

social behavior

GO:0043410

positive regulation of MAPKKK cascade

GO:0045740

positive regulation of DNA replication

GO:0048011

nerve growth factor receptor signaling pathway

GO:0050679

positive regulation of epithelial cell proliferation

GO:0050900

leukocyte migration

GO:0051291

protein heterooligomerization

GO:0070374

positive regulation of ERK1 and ERK2 cascade

GO:0090398

cellular senescence