HuLG002240

Entrez Gene ID

3275

Official Gene Symbol

PRMT2

Synonyms

HRMT1L1|MGC111373

Gene name

protein arginine methyltransferase 2

Gene Type

protein-coding

Chromosome

21

Genomics Location

21q22.3

Known cancer genes

Yes

Protein products

Protein arginine N-methyltransferase 2

Database cross reference

HGNC:5186
MIM:601961
Ensembl:ENSG00000160310
HPRD:09060
RefSeq Genomic nucleotide accession:AC_000064
RefSeq Genomic nucleotide gi:89161201

GO annotation

GO:0003713

transcription coactivator activity

GO:0004871

signal transducer activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006479

protein methylation

GO:0006917

induction of apoptosis

GO:0007165

signal transduction

GO:0008168

methyltransferase activity

GO:0008469

histone-arginine N-methyltransferase activity

GO:0016274

protein-arginine N-methyltransferase activity

GO:0016740

transferase activity

GO:0030331

estrogen receptor binding

GO:0032088

negative regulation of NF-kappaB transcription factor activity

GO:0033142

progesterone receptor binding

GO:0035189

Rb-E2F complex

GO:0035246

peptidyl-arginine N-methylation

GO:0042802

identical protein binding

GO:0042803

protein homodimerization activity

GO:0042974

retinoic acid receptor binding

GO:0042975

peroxisome proliferator activated receptor binding

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0046966

thyroid hormone receptor binding

GO:0048588

developmental cell growth

GO:0050681

androgen receptor binding

GO:0060765

regulation of androgen receptor signaling pathway

GO:2000134

negative regulation of G1/S transition of mitotic cell cycle