HuLG002246

Entrez Gene ID

3290

Official Gene Symbol

HSD11B1

Synonyms

11NDH|11NbetaNHSD1|HDL|HSD11|HSD11B|HSD11L|MGC13539|SDR26C1

Gene name

hydroxysteroid (11-beta) dehydrogenase 1

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q32-q41

Known cancer genes

Yes

Protein products

Corticosteroid 11-beta-dehydrogenase isozyme 1

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Fatty liver

Nonalcoholic steatohepatitis

Database cross reference

HGNC:5208
MIM:600713
Ensembl:ENSG00000117594
HPRD:07042
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0003845

11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity

GO:0005488

binding

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0006704

glucocorticoid biosynthetic process

GO:0008202

steroid metabolic process

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016491

oxidoreductase activity

GO:0030324

lung development

GO:0042446

hormone biosynthetic process

GO:0070524

11-beta-hydroxysteroid dehydrogenase (NADP+) activity