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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002250

Entrez Gene ID

3294

Official Gene Symbol

HSD17B2

Synonyms

EDH17B2|HSD17|SDR9C2

Gene name

hydroxysteroid (17-beta) dehydrogenase 2

Gene Type

protein-coding

Chromosome

16

Genomics Location

16q24.1-q24.2

Known cancer genes

Yes

Protein products

Estradiol 17-beta-dehydrogenase 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:5211
MIM:109685
Ensembl:ENSG00000086696
HPRD:00186
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004303

estradiol 17-beta-dehydrogenase activity

GO:0005488

binding

GO:0005789

endoplasmic reticulum membrane

GO:0006694

steroid biosynthetic process

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016491

oxidoreductase activity

GO:0032526

response to retinoic acid

GO:0047006

17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

GO:0050327

testosterone 17-beta-dehydrogenase (NAD+) activity