Gene basic information
| LiverAtlas Gene ID |
HuLG002262 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
HSPA5 |
|
Synonyms |
BIP|FLJ26106|GRP78|MIF2 |
|
Gene name |
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
|
Gene Type |
protein-coding |
|
Chromosome |
9 |
|
Genomics Location |
9q33.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:5238
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0002576 |
platelet degranulation |
|
GO:0005509 |
calcium ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005788 |
endoplasmic reticulum lumen |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005793 |
ER-Golgi intermediate compartment |
|
GO:0006200 |
ATP catabolic process |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006983 |
ER overload response |
|
GO:0006987 |
activation of signaling protein activity involved in unfolded protein response |
|
GO:0007596 |
blood coagulation |
|
GO:0008303 |
caspase complex |
|
GO:0009986 |
cell surface |
|
GO:0016887 |
ATPase activity |
|
GO:0019904 |
protein domain specific binding |
|
GO:0021589 |
cerebellum structural organization |
|
GO:0021680 |
cerebellar Purkinje cell layer development |
|
GO:0030168 |
platelet activation |
|
GO:0030176 |
integral to endoplasmic reticulum membrane |
|
GO:0030433 |
ER-associated protein catabolic process |
|
GO:0030496 |
midbody |
|
GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
|
GO:0030674 |
protein binding, bridging |
|
GO:0030968 |
endoplasmic reticulum unfolded protein response |
|
GO:0031398 |
positive regulation of protein ubiquitination |
|
GO:0031625 |
ubiquitin protein ligase binding |
|
GO:0034663 |
endoplasmic reticulum chaperone complex |
|
GO:0042149 |
cellular response to glucose starvation |
|
GO:0042470 |
melanosome |
|
GO:0043022 |
ribosome binding |
|
GO:0043027 |
caspase inhibitor activity |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043154 |
negative regulation of caspase activity |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0051082 |
unfolded protein binding |
|
GO:0051087 |
chaperone binding |
|
GO:0051603 |
proteolysis involved in cellular protein catabolic process |
|
GO:0051787 |
misfolded protein binding |
|
GO:0060904 |
regulation of protein folding in endoplasmic reticulum |
