Gene basic information
| LiverAtlas Gene ID |
HuLG002304 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
IRF8 |
|
Synonyms |
HNICSBP|ICSBP|ICSBP1|IRFN8 |
|
Gene name |
interferon regulatory factor 8 |
|
Gene Type |
protein-coding |
|
Chromosome |
16 |
|
Genomics Location |
16q24.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:5358
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0003677 |
DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003705 |
sequence-specific enhancer binding RNA polymerase II transcription factor activity |
|
GO:0005634 |
nucleus |
|
GO:0006909 |
phagocytosis |
|
GO:0006955 |
immune response |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0030099 |
myeloid cell differentiation |
|
GO:0032729 |
positive regulation of interferon-gamma production |
|
GO:0032735 |
positive regulation of interleukin-12 production |
|
GO:0042742 |
defense response to bacterium |
|
GO:0042832 |
defense response to protozoan |
|
GO:0044130 |
negative regulation of growth of symbiont in host |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0060333 |
interferon-gamma-mediated signaling pathway |
|
GO:0060337 |
type I interferon-mediated signaling pathway |
|
GO:0071222 |
cellular response to lipopolysaccharide |
