Gene basic information
| LiverAtlas Gene ID |
HuLG002338 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
IFNAR2 |
|
Synonyms |
IFNNR|IFNNalphaNREC|IFNABR|IFNARB |
|
Gene name |
interferon (alpha, beta and omega) receptor 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
21 |
|
Genomics Location |
21q22.1|21q22.11 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:5433
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004872 |
receptor activity |
|
GO:0004905 |
type I interferon receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0007259 |
JAK-STAT cascade |
|
GO:0009615 |
response to virus |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0019901 |
protein kinase binding |
|
GO:0019962 |
type I interferon binding |
|
GO:0035455 |
response to interferon-alpha |
|
GO:0060337 |
type I interferon-mediated signaling pathway |
|
GO:0060338 |
regulation of type I interferon-mediated signaling pathway |
