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Gene basic information

LiverAtlas Gene ID

HuLG002339

Entrez Gene ID

3456

Official Gene Symbol

IFNB1

Synonyms

IFB|IFF|IFNB|MGC96956

Gene name

interferon, beta 1, fibroblast

Gene Type

protein-coding

Chromosome

9

Genomics Location

9p21

Known cancer genes

Yes

Protein products

Interferon beta

Interferon beta

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Database cross reference

HGNC:5434
MIM:147640
Ensembl:ENSG00000171855
HPRD:00972
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

 

Ontology annotation

GO ID

GO annotation

GO:0003714

transcription corepressor activity

GO:0005125

cytokine activity

GO:0005132

interferon-alpha/beta receptor binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006917

induction of apoptosis

GO:0006919

activation of caspase activity

GO:0007166

cell surface receptor linked signaling pathway

GO:0007596

blood coagulation

GO:0008285

negative regulation of cell proliferation

GO:0009615

response to virus

GO:0019221

cytokine-mediated signaling pathway

GO:0030101

natural killer cell activation

GO:0032897

negative regulation of viral transcription

GO:0042100

B cell proliferation

GO:0042742

defense response to bacterium

GO:0045071

negative regulation of viral genome replication

GO:0045089

positive regulation of innate immune response

GO:0045343

regulation of MHC class I biosynthetic process

GO:0045581

negative regulation of T cell differentiation

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046597

negative regulation of virion penetration into host cell

GO:0051607

defense response to virus

GO:0060337

type I interferon-mediated signaling pathway

GO:0060338

regulation of type I interferon-mediated signaling pathway

GO:0071360

cellular response to exogenous dsRNA

GO:2000552

negative regulation of T-helper 2 cell cytokine production