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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002350

Entrez Gene ID

3482

Official Gene Symbol

IGF2R

Synonyms

CD222|CIMPR|M6PNR|MPR1|MPRI

Gene name

insulin-like growth factor 2 receptor

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q26

Known cancer genes

Yes

Protein products

Insulin-like growth factor type 2 receptor

Insulin-like growth factor type II receptor

Cation-independent mannose-6-phosphate receptor

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:5467
MIM:147280
Ensembl:ENSG00000197081
HPRD:00928
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001948

glycoprotein binding

GO:0004872

receptor activity

GO:0005010

insulin-like growth factor receptor activity

GO:0005215

transporter activity

GO:0005515

protein binding

GO:0005520

insulin-like growth factor binding

GO:0005537

mannose binding

GO:0005624

membrane fraction

GO:0005634

nucleus

GO:0005641

nuclear envelope lumen

GO:0005737

cytoplasm

GO:0005765

lysosomal membrane

GO:0005768

endosome

GO:0005887

integral to plasma membrane

GO:0006898

receptor-mediated endocytosis

GO:0007165

signal transduction

GO:0009986

cell surface

GO:0016020

membrane

GO:0030139

endocytic vesicle

GO:0030140

trans-Golgi network transport vesicle

GO:0048009

insulin-like growth factor receptor signaling pathway

GO:0051219

phosphoprotein binding