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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002359

Entrez Gene ID

3491

Official Gene Symbol

CYR61

Synonyms

CCN1|GIG1|IGFBP10

Gene name

cysteine-rich, angiogenic inducer, 61

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p22.3

Known cancer genes

Yes

Protein products

Protein CYR61

CYR61 protein

CYR61 protein

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:2654
MIM:602369
Ensembl:ENSG00000142871
HPRD:09089
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001558

regulation of cell growth

GO:0001934

positive regulation of protein phosphorylation

GO:0002041

intussusceptive angiogenesis

GO:0003181

atrioventricular valve morphogenesis

GO:0003278

apoptosis involved in heart morphogenesis

GO:0003281

ventricular septum development

GO:0005178

integrin binding

GO:0005520

insulin-like growth factor binding

GO:0005576

extracellular region

GO:0006935

chemotaxis

GO:0008201

heparin binding

GO:0008283

cell proliferation

GO:0009653

anatomical structure morphogenesis

GO:0010518

positive regulation of phospholipase activity

GO:0010811

positive regulation of cell-substrate adhesion

GO:0030198

extracellular matrix organization

GO:0030335

positive regulation of cell migration

GO:0030513

positive regulation of BMP signaling pathway

GO:0033690

positive regulation of osteoblast proliferation

GO:0043065

positive regulation of apoptosis

GO:0043066

negative regulation of apoptosis

GO:0043280

positive regulation of caspase activity

GO:0044319

wound healing, spreading of cells

GO:0045669

positive regulation of osteoblast differentiation

GO:0045860

positive regulation of protein kinase activity

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0050840

extracellular matrix binding

GO:0051789

response to protein stimulus

GO:0060413

atrial septum morphogenesis

GO:0060591

chondroblast differentiation

GO:0060710

chorio-allantoic fusion

GO:0060716

labyrinthine layer blood vessel development

GO:0061036

positive regulation of cartilage development

GO:0070372

regulation of ERK1 and ERK2 cascade

GO:2000304

positive regulation of ceramide biosynthetic process