Gene basic information
| LiverAtlas Gene ID |
HuLG002379 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
IL1A |
|
Synonyms |
ILN1A|IL1|IL1NALPHA|IL1F1 |
|
Gene name |
interleukin 1, alpha |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q14 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:5991
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001660 |
fever generation |
|
GO:0001666 |
response to hypoxia |
|
GO:0005125 |
cytokine activity |
|
GO:0005149 |
interleukin-1 receptor binding |
|
GO:0005507 |
copper ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006954 |
inflammatory response |
|
GO:0006955 |
immune response |
|
GO:0008283 |
cell proliferation |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009986 |
cell surface |
|
GO:0010193 |
response to ozone |
|
GO:0010243 |
response to organic nitrogen |
|
GO:0010332 |
response to gamma radiation |
|
GO:0010575 |
positive regulation vascular endothelial growth factor production |
|
GO:0010893 |
positive regulation of steroid biosynthetic process |
|
GO:0014070 |
response to organic cyclic compound |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0031424 |
keratinization |
|
GO:0032496 |
response to lipopolysaccharide |
|
GO:0032755 |
positive regulation of interleukin-6 production |
|
GO:0032874 |
positive regulation of stress-activated MAPK cascade |
|
GO:0033591 |
response to L-ascorbic acid |
|
GO:0034605 |
cellular response to heat |
|
GO:0042060 |
wound healing |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0045086 |
positive regulation of interleukin-2 biosynthetic process |
|
GO:0045766 |
positive regulation of angiogenesis |
|
GO:0045840 |
positive regulation of mitosis |
|
GO:0046330 |
positive regulation of JNK cascade |
|
GO:0046688 |
response to copper ion |
|
GO:0050715 |
positive regulation of cytokine secretion |
|
GO:0051781 |
positive regulation of cell division |
|
GO:0051930 |
regulation of sensory perception of pain |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
