Gene basic information
| LiverAtlas Gene ID |
HuLG002380 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
IL1B |
|
Synonyms |
ILN1|IL1NBETA|IL1F2 |
|
Gene name |
interleukin 1, beta |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q14 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:5992
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0001666 |
response to hypoxia |
|
GO:0001934 |
positive regulation of protein phosphorylation |
|
GO:0002439 |
chronic inflammatory response to antigenic stimulus |
|
GO:0002711 |
positive regulation of T cell mediated immunity |
|
GO:0005125 |
cytokine activity |
|
GO:0005149 |
interleukin-1 receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006954 |
inflammatory response |
|
GO:0006955 |
immune response |
|
GO:0007165 |
signal transduction |
|
GO:0007204 |
elevation of cytosolic calcium ion concentration |
|
GO:0007267 |
cell-cell signaling |
|
GO:0007566 |
embryo implantation |
|
GO:0007568 |
aging |
|
GO:0007584 |
response to nutrient |
|
GO:0007613 |
memory |
|
GO:0008083 |
growth factor activity |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009408 |
response to heat |
|
GO:0010193 |
response to ozone |
|
GO:0010243 |
response to organic nitrogen |
|
GO:0010332 |
response to gamma radiation |
|
GO:0010575 |
positive regulation vascular endothelial growth factor production |
|
GO:0010829 |
negative regulation of glucose transport |
|
GO:0014050 |
negative regulation of glutamate secretion |
|
GO:0014070 |
response to organic cyclic compound |
|
GO:0014805 |
smooth muscle adaptation |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0019904 |
protein domain specific binding |
|
GO:0030141 |
stored secretory granule |
|
GO:0030593 |
neutrophil chemotaxis |
|
GO:0030728 |
ovulation |
|
GO:0030730 |
sequestering of triglyceride |
|
GO:0031622 |
positive regulation of fever generation |
|
GO:0031982 |
vesicle |
|
GO:0032308 |
positive regulation of prostaglandin secretion |
|
GO:0032355 |
response to estradiol stimulus |
|
GO:0032496 |
response to lipopolysaccharide |
|
GO:0032725 |
positive regulation of granulocyte macrophage colony-stimulating factor production |
|
GO:0032729 |
positive regulation of interferon-gamma production |
|
GO:0032755 |
positive regulation of interleukin-6 production |
|
GO:0032757 |
positive regulation of interleukin-8 production |
|
GO:0032874 |
positive regulation of stress-activated MAPK cascade |
|
GO:0033129 |
positive regulation of histone phosphorylation |
|
GO:0033198 |
response to ATP |
|
GO:0033280 |
response to vitamin D |
|
GO:0033591 |
response to L-ascorbic acid |
|
GO:0034116 |
positive regulation of heterotypic cell-cell adhesion |
|
GO:0035066 |
positive regulation of histone acetylation |
|
GO:0035176 |
social behavior |
|
GO:0035505 |
positive regulation of myosin light chain kinase activity |
|
GO:0035690 |
cellular response to drug |
|
GO:0042060 |
wound healing |
|
GO:0042102 |
positive regulation of T cell proliferation |
|
GO:0042346 |
positive regulation of NF-kappaB import into nucleus |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043122 |
regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043278 |
response to morphine |
|
GO:0043407 |
negative regulation of MAP kinase activity |
|
GO:0043507 |
positive regulation of JUN kinase activity |
|
GO:0045080 |
positive regulation of chemokine biosynthetic process |
|
GO:0045086 |
positive regulation of interleukin-2 biosynthetic process |
|
GO:0045410 |
positive regulation of interleukin-6 biosynthetic process |
|
GO:0045429 |
positive regulation of nitric oxide biosynthetic process |
|
GO:0045766 |
positive regulation of angiogenesis |
|
GO:0045833 |
negative regulation of lipid metabolic process |
|
GO:0045840 |
positive regulation of mitosis |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046330 |
positive regulation of JNK cascade |
|
GO:0046627 |
negative regulation of insulin receptor signaling pathway |
|
GO:0046827 |
positive regulation of protein export from nucleus |
|
GO:0050796 |
regulation of insulin secretion |
|
GO:0050900 |
leukocyte migration |
|
GO:0050995 |
negative regulation of lipid catabolic process |
|
GO:0050996 |
positive regulation of lipid catabolic process |
|
GO:0051044 |
positive regulation of membrane protein ectodomain proteolysis |
|
GO:0051091 |
positive regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051384 |
response to glucocorticoid stimulus |
|
GO:0051781 |
positive regulation of cell division |
|
GO:0060355 |
positive regulation of cell adhesion molecule production |
|
GO:0060559 |
positive regulation of calcidiol 1-monooxygenase activity |
|
GO:0070164 |
negative regulation of adiponectin secretion |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
|
GO:0071260 |
cellular response to mechanical stimulus |
|
GO:0071310 |
cellular response to organic substance |
|
GO:0071639 |
positive regulation of monocyte chemotactic protein-1 production |
