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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002381

Entrez Gene ID

3554

Official Gene Symbol

IL1R1

Synonyms

CD121A|D2S1473|ILN1RNalpha|IL1R|IL1RA|P80

Gene name

interleukin 1 receptor, type I

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q12

Known cancer genes

Yes

Protein products

Interleukin-1 receptor type 1

Interleukin 1 receptor, type I

Interleukin 1 receptor, type I

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:5993
MIM:147810
Ensembl:ENSG00000115594
HPRD:00994
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004871

signal transducer activity

GO:0004888

transmembrane receptor activity

GO:0004908

interleukin-1 receptor activity

GO:0004909

interleukin-1, Type I, activating receptor activity

GO:0005161

platelet-derived growth factor receptor binding

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006955

immune response

GO:0007166

cell surface receptor linked signaling pathway

GO:0009986

cell surface

GO:0016020

membrane

GO:0030728

ovulation

GO:0045087

innate immune response

GO:0070498

interleukin-1-mediated signaling pathway

GO:0070555

response to interleukin-1

GO:0071731

response to nitric oxide