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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002383

Entrez Gene ID

3557

Official Gene Symbol

IL1RN

Synonyms

DIRA|ICILN1RA|ILN1RN|ILN1ra|ILN1ra3|IL1F3|IL1RA|IRAP|MGC10430|MVCD4

Gene name

interleukin 1 receptor antagonist

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q14.2

Known cancer genes

Yes

Protein products

Interleukin-1 receptor antagonist protein

Putative uncharacterized protein IL1RN

Type II interleukin-1 receptor antagonist

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Alcoholic liver cirrhosis

Biliary cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Liver fibrosis and liver cirrhosis caused by hepatitis B infection

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Database cross reference

HGNC:6000
MIM:147679
Ensembl:ENSG00000136689
HPRD:00978
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001960

negative regulation of cytokine-mediated signaling pathway

GO:0005125

cytokine activity

GO:0005152

interleukin-1 receptor antagonist activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005813

centrosome

GO:0005886

plasma membrane

GO:0006954

inflammatory response

GO:0006955

immune response

GO:0051384

response to glucocorticoid stimulus