Gene basic information
LiverAtlas Gene ID |
HuLG002383 |
Entrez Gene ID |
|
Official Gene Symbol |
IL1RN |
Synonyms |
DIRA|ICILN1RA|ILN1RN|ILN1ra|ILN1ra3|IL1F3|IL1RA|IRAP|MGC10430|MVCD4 |
Gene name |
interleukin 1 receptor antagonist |
Gene Type |
protein-coding |
Chromosome |
2 |
Genomics Location |
2q14.2 |
Known cancer genes |
Yes |
Protein products |
Interleukin-1 receptor antagonist protein |
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
Database cross reference |
HGNC:6000
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001960 |
negative regulation of cytokine-mediated signaling pathway |
GO:0005125 |
cytokine activity |
GO:0005152 |
interleukin-1 receptor antagonist activity |
GO:0005515 |
protein binding |
GO:0005576 |
extracellular region |
GO:0005615 |
extracellular space |
GO:0005622 |
intracellular |
GO:0005634 |
nucleus |
GO:0005737 |
cytoplasm |
GO:0005813 |
centrosome |
GO:0005886 |
plasma membrane |
GO:0006954 |
inflammatory response |
GO:0006955 |
immune response |
GO:0051384 |
response to glucocorticoid stimulus |