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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002384

Entrez Gene ID

3558

Official Gene Symbol

IL2

Synonyms

ILN2|TCGF|lymphokine

Gene name

interleukin 2

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q26-q27

Known cancer genes

Yes

Protein products

Interleukin-2

Interleukin 2

Interleukin 2

IL-2 protein

Interleukin 2

Interleukin 2

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Primary sclerosing cholangitis

Database cross reference

HGNC:6001
MIM:147680
Ensembl:ENSG00000109471
HPRD:00979
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001933

negative regulation of protein phosphorylation

GO:0001934

positive regulation of protein phosphorylation

GO:0002903

negative regulation of B cell apoptosis

GO:0005125

cytokine activity

GO:0005134

interleukin-2 receptor binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006916

anti-apoptosis

GO:0006955

immune response

GO:0007155

cell adhesion

GO:0007204

elevation of cytosolic calcium ion concentration

GO:0007205

activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway

GO:0007267

cell-cell signaling

GO:0008083

growth factor activity

GO:0008284

positive regulation of cell proliferation

GO:0019209

kinase activator activity

GO:0030101

natural killer cell activation

GO:0030217

T cell differentiation

GO:0030246

carbohydrate binding

GO:0030307

positive regulation of cell growth

GO:0030890

positive regulation of B cell proliferation

GO:0031851

kappa-type opioid receptor binding

GO:0032740

positive regulation of interleukin-17 production

GO:0034105

positive regulation of tissue remodeling

GO:0042104

positive regulation of activated T cell proliferation

GO:0042327

positive regulation of phosphorylation

GO:0042523

positive regulation of tyrosine phosphorylation of Stat5 protein

GO:0043208

glycosphingolipid binding

GO:0045591

positive regulation of regulatory T cell differentiation

GO:0045822

negative regulation of heart contraction

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046013

regulation of T cell homeostatic proliferation

GO:0048304

positive regulation of isotype switching to IgG isotypes

GO:0050672

negative regulation of lymphocyte proliferation

GO:0050728

negative regulation of inflammatory response

GO:0050729

positive regulation of inflammatory response

GO:0051024

positive regulation of immunoglobulin secretion