Gene basic information
LiverAtlas Gene ID |
HuLG002384 |
Entrez Gene ID |
|
Official Gene Symbol |
IL2 |
Synonyms |
ILN2|TCGF|lymphokine |
Gene name |
interleukin 2 |
Gene Type |
protein-coding |
Chromosome |
4 |
Genomics Location |
4q26-q27 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:6001
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001933 |
negative regulation of protein phosphorylation |
GO:0001934 |
positive regulation of protein phosphorylation |
GO:0002903 |
negative regulation of B cell apoptosis |
GO:0005125 |
cytokine activity |
GO:0005134 |
interleukin-2 receptor binding |
GO:0005576 |
extracellular region |
GO:0005615 |
extracellular space |
GO:0006916 |
anti-apoptosis |
GO:0006955 |
immune response |
GO:0007155 |
cell adhesion |
GO:0007204 |
elevation of cytosolic calcium ion concentration |
GO:0007205 |
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway |
GO:0007267 |
cell-cell signaling |
GO:0008083 |
growth factor activity |
GO:0008284 |
positive regulation of cell proliferation |
GO:0019209 |
kinase activator activity |
GO:0030101 |
natural killer cell activation |
GO:0030217 |
T cell differentiation |
GO:0030246 |
carbohydrate binding |
GO:0030307 |
positive regulation of cell growth |
GO:0030890 |
positive regulation of B cell proliferation |
GO:0031851 |
kappa-type opioid receptor binding |
GO:0032740 |
positive regulation of interleukin-17 production |
GO:0034105 |
positive regulation of tissue remodeling |
GO:0042104 |
positive regulation of activated T cell proliferation |
GO:0042327 |
positive regulation of phosphorylation |
GO:0042523 |
positive regulation of tyrosine phosphorylation of Stat5 protein |
GO:0043208 |
glycosphingolipid binding |
GO:0045591 |
positive regulation of regulatory T cell differentiation |
GO:0045822 |
negative regulation of heart contraction |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046013 |
regulation of T cell homeostatic proliferation |
GO:0048304 |
positive regulation of isotype switching to IgG isotypes |
GO:0050672 |
negative regulation of lymphocyte proliferation |
GO:0050728 |
negative regulation of inflammatory response |
GO:0050729 |
positive regulation of inflammatory response |
GO:0051024 |
positive regulation of immunoglobulin secretion |