Gene basic information
| LiverAtlas Gene ID |
HuLG002389 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
IL4 |
|
Synonyms |
BCGFN1|BCGF1|BSFN1|BSF1|ILN4|MGC79402 |
|
Gene name |
interleukin 4 |
|
Gene Type |
protein-coding |
|
Chromosome |
5 |
|
Genomics Location |
5q31.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:6014
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002674 |
negative regulation of acute inflammatory response |
|
GO:0002677 |
negative regulation of chronic inflammatory response |
|
GO:0005125 |
cytokine activity |
|
GO:0005136 |
interleukin-4 receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0006935 |
chemotaxis |
|
GO:0006955 |
immune response |
|
GO:0006968 |
cellular defense response |
|
GO:0007565 |
female pregnancy |
|
GO:0007584 |
response to nutrient |
|
GO:0008083 |
growth factor activity |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0010155 |
regulation of proton transport |
|
GO:0014070 |
response to organic cyclic compound |
|
GO:0030183 |
B cell differentiation |
|
GO:0030890 |
positive regulation of B cell proliferation |
|
GO:0032733 |
positive regulation of interleukin-10 production |
|
GO:0032736 |
positive regulation of interleukin-13 production |
|
GO:0034097 |
response to cytokine stimulus |
|
GO:0035745 |
T-helper 2 cell cytokine production |
|
GO:0042092 |
type 2 immune response |
|
GO:0042102 |
positive regulation of T cell proliferation |
|
GO:0042104 |
positive regulation of activated T cell proliferation |
|
GO:0042325 |
regulation of phosphorylation |
|
GO:0042493 |
response to drug |
|
GO:0042523 |
positive regulation of tyrosine phosphorylation of Stat5 protein |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0045019 |
negative regulation of nitric oxide biosynthetic process |
|
GO:0045189 |
connective tissue growth factor biosynthetic process |
|
GO:0045191 |
regulation of isotype switching |
|
GO:0045348 |
positive regulation of MHC class II biosynthetic process |
|
GO:0045471 |
response to ethanol |
|
GO:0045582 |
positive regulation of T cell differentiation |
|
GO:0045671 |
negative regulation of osteoclast differentiation |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0048295 |
positive regulation of isotype switching to IgE isotypes |
|
GO:0048304 |
positive regulation of isotype switching to IgG isotypes |
|
GO:0050727 |
regulation of inflammatory response |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0050776 |
regulation of immune response |
|
GO:0051091 |
positive regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0071288 |
cellular response to mercury ion |
