Gene basic information
LiverAtlas Gene ID |
HuLG002390 |
Entrez Gene ID |
|
Official Gene Symbol |
IL4R |
Synonyms |
CD124|IL4RA |
Gene name |
interleukin 4 receptor |
Gene Type |
protein-coding |
Chromosome |
16 |
Genomics Location |
16p12.1-p11.2 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:6015
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0002532 |
production of molecular mediator involved in inflammatory response |
GO:0004872 |
receptor activity |
GO:0004913 |
interleukin-4 receptor activity |
GO:0005057 |
receptor signaling protein activity |
GO:0005515 |
protein binding |
GO:0005576 |
extracellular region |
GO:0005615 |
extracellular space |
GO:0005886 |
plasma membrane |
GO:0005887 |
integral to plasma membrane |
GO:0006955 |
immune response |
GO:0007165 |
signal transduction |
GO:0035771 |
interleukin-4-mediated signaling pathway |
GO:0042127 |
regulation of cell proliferation |
GO:0042802 |
identical protein binding |
GO:0043032 |
positive regulation of macrophage activation |
GO:0043560 |
insulin receptor substrate binding |
GO:0045626 |
negative regulation of T-helper 1 cell differentiation |
GO:0045630 |
positive regulation of T-helper 2 cell differentiation |
GO:0090197 |
positive regulation of chemokine secretion |