HuLG002398

Entrez Gene ID

3576

Official Gene Symbol

IL8

Synonyms

CXCL8|GCPN1|GCP1|LECT|LUCT|LYNAP|MDNCF|MONAP|NAF|NAPN1|NAP1

Gene name

interleukin 8

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q13-q21

Known cancer genes

Yes

Protein products

Interleukin-8

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Alcoholic hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Primary sclerosing cholangitis

Database cross reference

HGNC:6025
MIM:146930
Ensembl:ENSG00000169429
HPRD:00909
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0001525

angiogenesis

GO:0002237

response to molecule of bacterial origin

GO:0005153

interleukin-8 receptor binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006928

cellular component movement

GO:0006935

chemotaxis

GO:0006954

inflammatory response

GO:0006955

immune response

GO:0007050

cell cycle arrest

GO:0007165

signal transduction

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0008009

chemokine activity

GO:0008285

negative regulation of cell proliferation

GO:0019722

calcium-mediated signaling

GO:0030155

regulation of cell adhesion

GO:0030593

neutrophil chemotaxis

GO:0035556

intracellular signal transduction

GO:0042119

neutrophil activation

GO:0045091

regulation of retroviral genome replication

GO:0048566

embryonic digestive tract development

GO:0050930

induction of positive chemotaxis

GO:0071222

cellular response to lipopolysaccharide

GO:0090023

positive regulation of neutrophil chemotaxis