Gene basic information
| LiverAtlas Gene ID |
HuLG002403 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
IL10 |
|
Synonyms |
CSIF|ILN10|IL10A|MGC126450|MGC126451|TGIF |
|
Gene name |
interleukin 10 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q31-q32 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection |
|
Database cross reference |
HGNC:5962
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002237 |
response to molecule of bacterial origin |
|
GO:0002740 |
negative regulation of cytokine secretion involved in immune response |
|
GO:0002875 |
negative regulation of chronic inflammatory response to antigenic stimulus |
|
GO:0002904 |
positive regulation of B cell apoptosis |
|
GO:0005125 |
cytokine activity |
|
GO:0005141 |
interleukin-10 receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006950 |
response to stress |
|
GO:0006954 |
inflammatory response |
|
GO:0007253 |
cytoplasmic sequestering of NF-kappaB |
|
GO:0007267 |
cell-cell signaling |
|
GO:0008083 |
growth factor activity |
|
GO:0010468 |
regulation of gene expression |
|
GO:0014823 |
response to activity |
|
GO:0030097 |
hemopoiesis |
|
GO:0030183 |
B cell differentiation |
|
GO:0030595 |
leukocyte chemotaxis |
|
GO:0030886 |
negative regulation of myeloid dendritic cell activation |
|
GO:0030889 |
negative regulation of B cell proliferation |
|
GO:0032496 |
response to lipopolysaccharide |
|
GO:0032689 |
negative regulation of interferon-gamma production |
|
GO:0032695 |
negative regulation of interleukin-12 production |
|
GO:0032715 |
negative regulation of interleukin-6 production |
|
GO:0032720 |
negative regulation of tumor necrosis factor production |
|
GO:0032800 |
receptor biosynthetic process |
|
GO:0032868 |
response to insulin stimulus |
|
GO:0034465 |
response to carbon monoxide |
|
GO:0042092 |
type 2 immune response |
|
GO:0042100 |
B cell proliferation |
|
GO:0042130 |
negative regulation of T cell proliferation |
|
GO:0042493 |
response to drug |
|
GO:0042536 |
negative regulation of tumor necrosis factor biosynthetic process |
|
GO:0042742 |
defense response to bacterium |
|
GO:0044130 |
negative regulation of growth of symbiont in host |
|
GO:0045019 |
negative regulation of nitric oxide biosynthetic process |
|
GO:0045191 |
regulation of isotype switching |
|
GO:0045347 |
negative regulation of MHC class II biosynthetic process |
|
GO:0045348 |
positive regulation of MHC class II biosynthetic process |
|
GO:0045355 |
negative regulation of interferon-alpha biosynthetic process |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0050715 |
positive regulation of cytokine secretion |
|
GO:0050728 |
negative regulation of inflammatory response |
|
GO:0051045 |
negative regulation of membrane protein ectodomain proteolysis |
|
GO:0051091 |
positive regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0051384 |
response to glucocorticoid stimulus |
|
GO:0051930 |
regulation of sensory perception of pain |
|
GO:0060670 |
branching involved in embryonic placenta morphogenesis |
|
GO:0071392 |
cellular response to estradiol stimulus |
